Decolonization of intestinal carriage of extended-spectrum b-lactamase-producing Enterobacteriaceae with oral colistin and neomycin: a randomized, double-blind, placebo-controlled trial
نویسندگان
چکیده
Infection Control Program, Geneva University Hospital and Faculty of Medicine, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 4, Switzerland; Clinical Microbiology Laboratory, Service of Infectious Diseases, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 4, Switzerland; Pharmacy, Geneva University Hospital, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 4, Switzerland; Assistance publique— Hôpitaux de Paris (AP-HP) and University Paris-Diderot Medical School, Paris, France
منابع مشابه
Decolonization of intestinal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae with oral colistin and neomycin: a randomized, double-blind, placebo-controlled trial.
OBJECTIVES Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) are an increasingly frequent cause of infections in the community and the healthcare setting. In this study, we aimed to investigate whether intestinal carriage of ESBL-E can be eradicated. METHODS We conducted a double-blind, randomized, placebo-controlled, single-centre trial to assess the efficacy of an oral dec...
متن کاملIntestinal decolonization of Enterobacteriaceae producing extended-spectrum β-lactamases (ESBL): a retrospective observational study in patients at risk for infection and a brief review of the literature
BACKGROUND Multidrug-resistant Escherichia coli and other enteric bacteria producing extended-spectrum β-lactamases (ESBL) have emerged as an important cause of invasive infection. Targeting the primary (intestinal) niche by decolonization may be a valuable approach to decrease the risk of relapsing infections and to reduce transmission of ESBL-producing enteric pathogens. METHODS In a retros...
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تاریخ انتشار 2013